Smart, Living & Active Matter - Leiden

Leiden Institute of Physics

About us

The SLAM - Smart, Living, & Active Matter - initiative unites theory and experimental groups of the Leiden Institute of Physics. It currently gathers the groups of Luca Giomi, Louise Jawerth, Daniela Kraft, Martin van Hecke, Silke Henkes and Alexandre Morin.

Coming up next


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2026-10-29 - 13:30 @ DM1.19 (New Gorleaus)

SLAM Seminar Tannie Liverpool (University of Bristol)

The mathematics  and physics of wound healing 


I will discuss some recent work looking quantitatively at the process of wound healing using ideas from thermodynamics, continuum and statistical mechanics. Wound healing is a highly conserved process required for survival of an animal after tissue damage. The wound repair process is not only of great interest in its own right but is also a laboratory to study complex tissue dynamics and regeneration.

Many wounds involve damage to an epithelial (barrier) tissue (like skin) that separates different regions of the body of a living organism. I will describe some recent work on studying wound healing in two dimensional epithelial tissues of a fruit fly pupal wing. This epithelium was chosen because it is transparent and accessible to sophisticated imaging techniques. We use live confocal time-lapse microscopy to follow the behaviour of cells in a tissue before and after wounding.

I will focus on three cell-behaviours that are generally accepted to contribute to wound re-epithelialisation: cell shape deformation, cell division, and cell migration.

I will describe how we are beginning to use a combination of mathematics, physics and biology to disentangle some of the organising principles behind the complex orchestrated dynamics that lead to wound healing.